Does Poor Mental Health run in the family?
When you sign up for a new doctor, fill in a medical form for a new job or even apply for travel insurance for your next summer holiday you’re usually asked whether a number of physical conditions such as heart disease, diabetes or common cancers have affected your immediate family members in order to give your doctor/employer/insurer a better idea of your overall physical health.
Biologically we’re closer to our immediate family, than any other person on the planet – even family we have never lived with, or even met – due to our unique genetic make-up. But what about our mental health?
Is Mental Health Hereditary?
Over the past few years the idea of whether or not poor mental health runs in families has been greatly explored, with many studies suggesting that parents who suffer with mental health issues, often find their children also struggle with similar problems. But is it a behaviour we have learned from our loved ones, or something we have inherited biologically?
Nature verses Nurture
Ever opened your mouth and heard your mum’s voice come out? – A lot of us are more similar to our parents than we would like to admit. Whilst our likes, dislikes and preferences may differ – often the family we grow up around and the people we live with shape our futures in ways we might not realise.
When it comes to mental health running in families, previously it has been difficult to determine whether or not we have simply learned the behaviour through primary and secondary socialisation, or whether or not it was passed onto us from our parents in the same way that heart disease and other physical health problems can be hereditary.
Most recently, a study in the UK found that Dads who suffer with post-natal depression are more likely to have daughters with mental health issues when they reach 18 years of age. However, the study found that boys with fathers who suffered the same mental health issue, were often unaffected – suggesting it is a behavioural trait that is possibly linked to specific aspects of a father daughter relationship throughout adolescence, rather than a biological factor.
However, a number of other studies have suggested that like some physical conditions, mental health can be passed on from parent to child in the same way that diabetes or heart disease might be – especially when it comes to long term mental health conditions such as bipolar disorder or clinical depression.
What do we Know So Far?
Sky News recently reported that five well-known mental health conditions – including autism, attention deficit hyperactivity disorder, clinical depression, bipolar disorder and schizophrenia – were found to be genetically linked. The study examined the genetic sequences of over 50,000 people – 30,000 people who suffer with one of the conditions mentioned above and 27,000 who didn’t have any of the conditions. The study concluded that all five conditions may share common genetic risk factors – suggesting that these particular mental health conditions can, in fact, be passed on genetically from parent to child. Researchers stated that at this stage it is still unknown whether or not more common mental health conditions such as depression or generalised anxiety disorder also share genetic variations.
King’s College London (KCL) have also been exploring the relation between genetics and mental health, with a number of different studies taking place over the last few years which have proved a genetic contribution towards poor mental health. Often physical conditions that are passed on genetically are carried on one single gene, however mental health conditions are often carried on a group or combination of different genes – making it a lot more difficult to study the connection between parent and child.
Staff at KCL are in the very early stages of further exploring the genetic aspect of mental health issues and identifying the effected genes – however as Professor Cathryn Lewis of the NIHR Maudsley Biomedical Research Centre explains “It’s really hard to identify the genetics for mental health disorders. We learn at school about simple Mendelian [relating to the laws of Gregor Mendel] diseases – like Huntington’s or cystic fibrosis – where there is the gene, a single gene that contributes to it. Mental health disorders are not about a single gene but about a collection of genes. We need to start thinking about this as a cumulative loading of genetics.”
Whilst research is still in the very early stages, it has already found over 108 gene changes in those who suffer with schizophrenia, nine in those who suffer with depression and 20 in people who suffer with bipolar disorder – with scientists expecting to find many more throughout the study. Once we have a better understanding of how mental health issues can be passed on from parent to child, it could make both diagnosing and treating mental health conditions much easier in the future.
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